Description: Recombinant Human SMPDL3A Protein is produced by mammalian expression system and the target gene encoding Leu23-Tyr453 is expressed with a 6His tag at the C-terminus. Form: Lyophilized from a 0.2 μM filtered solution of PBS, pH 7.4. Gene Symbol: SMPDL3A Alternative Names: ASML3A; Acid sphingomyelinase-like phosphodiesterase 3a; ASM-like phosphodiesterase 3aEntrez Gene (Human): 10924SwissProt (Human): Q92484Purity : Greater than 95% as determined by reducing SDS-PAGE.Chemical Structure : LPVAPAGGRN PPPAIGQFWH VTDLHLDPTY HITDDHTKVC ASSKGANASN PGPFGDVLCD SPYQLILSAF DFIKNSGQEA SFMIWTGDSP PHVPVPELST DTVINVITNM TTTIQSLFPN LQVFPALGNH DYWPQDQLPV VTSKVYNAVA NLWKPWLDEE AISTLRKGGF YSQKVTTNPN LRIISLNTNL YYGPNIMTLN KTDPANQFEW LESTLNNSQQ NKEKVYIIAH VPVGYLPSSQ NITAMREYYN EKLIDIFQKY SDVIAGQFYG HTHRDSIMVL SDKKGSPVNS LFVAPAVTPV KSVLEKQTNN PGIRLFQYDP RDYKLLDMLQ YYLNLTEANL KGESIWKLEY ILTQTYDIED LQPESLYGLA KQFTILDSKQ FIKYYNYFFV SYDSSVTCDK TCKAFQICAI MNLDNISYAD CLKQLYIKHN YVDHHHHHH Directions for Use : Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Quality Control : Endotoxin: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.Storage/Stability : Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.