Description: Rabbit polyclonal antibody to HMGCR Immunogen: Recombinant full length protein of human HMGCR Purification: The antibody was purified by immunogen affinity chromatography. Clonality: Polyclonal Form: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. Dilution: WB (1/500 - 1/1000), IH (1/50 - 1/100) Gene Symbol: HMGCR Alternative Names: 3-hydroxy-3-methylglutaryl-coenzyme A reductase; HMG-CoA reductaseEntrez Gene (Human): 3156Entrez Gene (Mouse) : 15357Entrez Gene (Rat) : 25675SwissProt (Human): P04035SwissProt (Mouse) : Q01237SwissProt (Rat) : P51639Storage/Stability : Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
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Western blot analysis of HMGCR expression in HepG2 (A), Hela (B), mouse spleen (C), rat liver (D) whole cell lysates.
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Immunohistochemical analysis of HMGCR staining in human small intestine formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Arachidonic acid is associated with dyslipidemia and cholesterol-related lipoprotein metabolism signatures