Description: Rabbit polyclonal antibody to Presenilin 1 (Phospho-S357) Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding S357 of human Presenilin 1 protein. The exact sequence is proprietary. Purification: The antibody was purified by immunogen affinity chromatography. Clonality: Polyclonal Form: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. Dilution: WB (1/500 - 1/1000), IH (1/50 - 1/200) Gene Symbol: PSEN1 Alternative Names: AD3; PS1; PSNL1; Presenilin-1; PS-1; Protein S182Entrez Gene (Human): 5663Entrez Gene (Mouse) : 19164Entrez Gene (Rat) : 29192SwissProt (Human): P49768SwissProt (Mouse) : P49769SwissProt (Rat) : P97887Storage/Stability : Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

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  Western blot analysis of Presenilin 1 (Phospho-S357) expression in HCT116 (A), Beas2B (B), mouse embryo (C), rat brain (D) whole cell lysates.
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  Immunohistochemical analysis of Presenilin 1 (Phospho-S357) staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.