Description: Rabbit polyclonal antibody to Nav1.2 Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Nav1.2. The exact sequence is proprietary. Purification: The antibody was purified by immunogen affinity chromatography. Clonality: Polyclonal Form: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. Dilution: WB (1/500 - 1/1000), IH (1/50 - 1/200) Gene Symbol: SCN2A Alternative Names: NAC2; SCN2A1; SCN2A2; Sodium channel protein type 2 subunit alpha; HBSC II; Sodium channel protein brain II subunit alpha; Sodium channel protein type II subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.2Entrez Gene (Human): 6326Entrez Gene (Rat) : 24766SwissProt (Human): Q99250SwissProt (Rat) : P04775Storage/Stability : Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
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Western blot analysis of Nav1.2 expression in C6 (A), BV2 (B), rat brain (C), mouse brain (D), HEK293T (E), LO2 (F) whole cell lysates.
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Immunohistochemical analysis of Nav1.2 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.