Description: Rabbit polyclonal antibody to STAT2 Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human STAT2. The exact sequence is proprietary. Purification: The antibody was purified by immunogen affinity chromatography. Clonality: Polyclonal Form: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. Dilution: WB (1/500 - 1/1000), IH (1/100 - 1/200) Gene Symbol: STAT2 Alternative Names: Signal transducer and activator of transcription 2; p113Entrez Gene (Human): 6773SwissProt (Human): P52630SwissProt (Mouse) : Q9WVL2Storage/Stability : Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
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Western blot analysis of STAT2 expression in HeLa (A), HepG2 (B) whole cell lysates.
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Immunohistochemical analysis of STAT2 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
IFNgamma mediates DUOX2 expression via a STAT-independent signaling pathway