Description: Rabbit polyclonal antibody to STAT2 (Phospho-Y690) Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding Y690 of human STAT2 protein. The exact sequence is proprietary. Purification: The antibody was purified by immunogen affinity chromatography. Clonality: Polyclonal Form: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. Dilution: WB (1/500 - 1/1000), IH (1/100 - 1/200) Gene Symbol: STAT2 Alternative Names: Signal transducer and activator of transcription 2; p113Entrez Gene (Human): 6773SwissProt (Human): P52630SwissProt (Mouse) : Q9WVL2Storage/Stability : Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
-
Western blot analysis of STAT2 (Phospho-Y690) expression in MCF7 (A), H446 (B), mouse liver (C), rat liver (D) whole cell lysates.
-
Immunohistochemical analysis of STAT2 (Phospho-Y690) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
IFNß autocrine feedback is required to sustain TLR induced production of MCP-1 in macrophages
Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma
Induction of Type I Interferon Signaling by Pseudomonas aeruginosa is Diminished in Cystic Fibrosis Epithelial Cells
Inducible microRNA-155 feedback promotes type I IFN signaling in antiviral innate immunity by targeting suppressor of cytokine signaling 1
IFNgamma mediates DUOX2 expression via a STAT-independent signaling pathway
A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses