Description: Rabbit polyclonal antibody to GNAT1 Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human GNAT1. The exact sequence is proprietary. Purification: The antibody was purified by immunogen affinity chromatography. Clonality: Polyclonal Form: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. Dilution: WB (1/500 - 1/1000), IH (1/100 - 1/200) Gene Symbol: GNAT1 Alternative Names: GNATR; Guanine nucleotide-binding protein G(t) subunit alpha-1; Transducin alpha-1 chainEntrez Gene (Human): 2779Entrez Gene (Mouse) : 14685SwissProt (Human): P11488SwissProt (Mouse) : P20612Storage/Stability : Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
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Western blot analysis of GNAT1 expression in mouse eyes (A), rat eyes (B) whole cell lysates.
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Immunohistochemical analysis of GNAT1 staining in human heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Leukemia Inhibitory Factor (LIF) coordinates the downregulation of the visual cycle in the retina and retinal pigmented epithelium (RPE)