Description: Rabbit polyclonal antibody to BTK (Phospho-Y551) Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding Y551 of human BTK protein. The exact sequence is proprietary. Purification: The antibody was purified by immunogen affinity chromatography. Clonality: Polyclonal Form: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. Dilution: WB (1/500 - 1/1000) Gene Symbol: BTK Alternative Names: AGMX1; ATK; BPK; Tyrosine-protein kinase BTK; Agammaglobulinemia tyrosine kinase; ATK; B-cell progenitor kinase; BPK; Bruton tyrosine kinaseEntrez Gene (Human): 695Entrez Gene (Mouse) : 12229SwissProt (Human): Q06187SwissProt (Mouse) : P35991Storage/Stability : Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
-
Western blot analysis of BTK (Phospho-Y551) expression in Jurkat (A), K562 (B) whole cell lysates.
Augmented TLR9-induced Btk activation in PIR-B-deficient B-1 cells provokes excessive autoantibody production and autoimmunity