Description: Rabbit polyclonal antibody to ODC Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ODC. The exact sequence is proprietary. Purification: The antibody was purified by immunogen affinity chromatography. Clonality: Polyclonal Form: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. Dilution: WB (1/500 - 1/1000), IH (1/100 - 1/200) Gene Symbol: SLC25A21 Alternative Names: ODC; Mitochondrial 2-oxodicarboxylate carrier; Solute carrier family 25 member 21Entrez Gene (Human): 89874SwissProt (Human): Q9BQT8Storage/Stability : Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
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Western blot analysis of ODC expression in Hela (A), HepG2 (B), LO2 (C), PC12 (D), AML12 (E) whole cell lysates.
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Immunohistochemical analysis of ODC staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Diabetic retinopathy and damage to mitochondrial structure and transport machinery