Anti-Topoisomerase 2 beta Antibody 
Datasheet
MSDS
Description: Rabbit polyclonal antibody to Topoisomerase 2 beta Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Topoisomerase 2 beta. The exact sequence is proprietary. Purification: The antibody was purified by immunogen affinity chromatography. Clonality: Polyclonal Form: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. Dilution: WB (1/500 - 1/1000), IH (1/50 - 1/100), ChIP (1/10 - 1/100) Gene Symbol: TOP2B Alternative Names: DNA topoisomerase 2-beta; DNA topoisomerase II, beta isozymeEntrez Gene (Human): 7155SwissProt (Human): Q02880Storage/Stability : Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
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Western blot analysis of Topoisomerase 2 beta expression in HEK293T (A), mouse testis (B) whole cell lysates. -
Immunohistochemical analysis of Topoisomerase 2 beta staining in human tonsil formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
DNA damage response (DDR) induced by topoisomerase II poisons requires nuclear function of the small GTPase Rac
TRF2 and Apollo Cooperate with Topoisomerase 2alpha to Protect Human Telomeres from Replicative Damage