Description: Rabbit polyclonal antibody to Nav1.7 Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Nav1.7. The exact sequence is proprietary. Purification: The antibody was purified by immunogen affinity chromatography. Clonality: Polyclonal Form: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. Dilution: WB (1/500 - 1/1000), IH (1/50 - 1/100), IF/IC (1/50 - 1/200) Gene Symbol: SCN9A Alternative Names: NENA; Sodium channel protein type 9 subunit alpha; Neuroendocrine sodium channel; hNE-Na; Peripheral sodium channel 1; PN1; Sodium channel protein type IX subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.7Entrez Gene (Human): 6335Entrez Gene (Rat) : 78956SwissProt (Human): Q15858SwissProt (Mouse) : Q62205SwissProt (Rat) : O08562Storage/Stability : Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
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Western blot analysis of Nav1.7 expression in mouse testis (A), rat testis (B), HCT116 (C), A549 (D) whole cell lysates.
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Immunohistochemical analysis of Nav1.7 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.