Description: Rabbit polyclonal antibody to Focal Adhesion Kinase (Phospho-Y576) Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding Y576 of human Focal Adhesion Kinase protein. The exact sequence is proprietary. Purification: The antibody was purified by immunogen affinity chromatography. Clonality: Polyclonal Form: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. Dilution: WB (1/500 - 1/1000) Gene Symbol: PTK2 Alternative Names: FAK; FAK1; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAKEntrez Gene (Human): 5747Entrez Gene (Mouse) : 14083Entrez Gene (Rat) : 25614SwissProt (Human): Q05397SwissProt (Mouse) : P34152SwissProt (Rat) : O35346Storage/Stability : Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
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Western blot analysis of Focal Adhesion Kinase (Phospho-Y576) expression in HEK293T Forskolin-treated (A), NIH3T3 Forskolin-treated (B), H9C2 Forskolin-treated (C) whole cell lysates.
Phase II trial of dasatinib in patients with metastatic breast cancer using real-time pharmacodynamic tissue biomarkers of Src inhibition to escalate dosing