Description: Rabbit polyclonal antibody to JAK2 Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human JAK2. The exact sequence is proprietary. Purification: The antibody was purified by immunogen affinity chromatography. Clonality: Polyclonal Form: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. Dilution: WB (1/500 - 1/1000) Gene Symbol: JAK2 Alternative Names: Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2Entrez Gene (Human): 3717Entrez Gene (Mouse) : 16452Entrez Gene (Rat) : 24514SwissProt (Human): O60674SwissProt (Mouse) : Q62120SwissProt (Rat) : Q62689Storage/Stability : Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
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Western blot analysis of JAK2 expression in HEK293T (A), SP2/0 (B), H9C2 (C) whole cell lysates.
The Jak/STAT pathway is involved in synaptic plasticity
Vascular smooth muscle Jak2 deletion prevents angiotensin II-mediated neointima formation following injury in mice
Vascular smooth muscle Jak2 mediates angiotensin II-induced hypertension via increased levels of reactive oxygen species