Description: Rabbit polyclonal antibody to GABBR1 Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human GABBR1. The exact sequence is proprietary. Purification: The antibody was purified by immunogen affinity chromatography. Clonality: Polyclonal Form: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. Dilution: WB (1/500 - 1/1000), IH (1/50 - 1/100) Gene Symbol: GABBR1 Alternative Names: GPRC3A; Gamma-aminobutyric acid type B receptor subunit 1; GABA-B receptor 1; GABA-B-R1; GABA-BR1; GABABR1; Gb1Entrez Gene (Human): 2550Entrez Gene (Mouse) : 54393Entrez Gene (Rat) : 81657SwissProt (Human): Q9UBS5SwissProt (Mouse) : Q9WV18SwissProt (Rat) : Q9Z0U4Storage/Stability : Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
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Western blot analysis of GABBR1 expression in HCT116 (A), PC3 (B), CT26 (C), H1792 (D) whole cell lysates.
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Immunohistochemical analysis of GABBR1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Molecular mechanisms underlying the enhanced analgesic effect of oxycodone compared to morphine in chemotherapy-induced neuropathic pain