Description: Rabbit polyclonal antibody to Filamin A Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Filamin A. The exact sequence is proprietary. Purification: The antibody was purified by immunogen affinity chromatography. Clonality: Polyclonal Form: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. Dilution: WB (1/500 - 1/1000), IH (1/100 - 1/200), IP (1/10 - 1/100) Gene Symbol: FLNA Alternative Names: FLN; FLN1; Filamin-A; FLN-A; Actin-binding protein 280; ABP-280; Alpha-filamin; Endothelial actin-binding protein; Filamin-1; Non-muscle filaminEntrez Gene (Human): 2316Entrez Gene (Mouse) : 192176SwissProt (Human): P21333SwissProt (Mouse) : Q8BTM8Storage/Stability : Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
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Western blot analysis of Filamin A expression in HEK293T (A), SP2/0 (B), rat heart (C) whole cell lysates.
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Immunohistochemical analysis of Filamin A staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Filamin-interacting proteins, Cfm1 and Cfm2, are essential for the formation of cartilaginous skeletal elements
RSK2 Protein Suppresses Integrin Activation and Fibronectin Matrix Assembly and Promotes Cell Migration
Enhancing the effectiveness of androgen deprivation in prostate cancer by inducing Filamin A nuclear localization
Filamin a protein interacts with human immunodeficiency virus type 1 gag protein and contributes to productive particle assembly
Filamin A is a phosphorylation target of membrane but not cytosolic adenylyl cyclase activity