Description: Anti-PD-L1 [Avelumab] Purification: Affinity Chromatography Clonality: Monoclonal Form: IgG1, liquid in 10 mmol/L PBS, pH 7.2 Gene Symbol: CD274 Alternative Names: B7H1; PDCD1L1; PDCD1LG1; PDL1; Programmed cell death 1 ligand 1; PD-L1; PDCD1 ligand 1; Programmed death ligand 1; B7 homolog 1; B7-H1; CD274Entrez Gene (Human): 29126SwissProt (Human): Q9NZQ7Components : Avelumab biosimilar is a programmed death ligand-1 (PD-L1) blocking antibody and prevents its interaction with the inhibitory T-cell receptor, PD-1 (programmed cell death protein 1). Upon binding, avelumab promotes T-cell reactivation and restores T-cell-mediated immune response against tumor cells. Avelumab is also the only PD-L1 antibody so far to also induce antibody-dependent cell-mediated cytotoxicity (ADCC) against tumor cells expressing PD-L1.Storage/Stability : Stored at 2-8°C for at least 4 weeks. Store at -20 °C for 12 months. For long term storage aseptically aliquot and store at -80°C. Avoid repeated freeze/thaw cycles.