Description: Anti-HER2 [Ado-trastuzumab emtansine] Purification: Affinity Chromatography Clonality: Monoclonal Form: IgG1, liquid in 10 mmol/L PBS, pH 7.2 Gene Symbol: ERBB2 Alternative Names: HER2; MLN19; NEU; NGL; Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD340Entrez Gene (Human): 2064SwissProt (Human): P04626Components : Ado-trastuzumab emtansine is a HER2-targeted antibody-drug conjugate which contains the humanized anti-HER2 IgG1, trastuzumab, covalently linked to the microtubule inhibitory drug DM1 via the stable thioether linker MCC. Trastuzumab is produced by Chinese hamster ovary cells, and DM1-MCC are produced by chemical synthesis. Ado-trastuzumab emtansine contains an average of 3.5 DM1 molecules per antibody.Storage/Stability : Stored at 2-8°C for at least 4 weeks. Store at -20 °C for 12 months. For long term storage aseptically aliquot and store at -80°C. Avoid repeated freeze/thaw cycles.