Description: Peptide to Biotin-[Pyr3]-Beta-Amyloid-Protein (3-42) Form: Lyophilized powder Molecular Formula : C196H299N53O55SMolecular Weight : 4309.97Purity : > 95%Chemical Structure : Biotin-Pyr-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-AlaApplication : [Pyr3]-Beta-Amyloid-Protein (3-42) was found to be the predominant amyloid β-peptide structure deposited in human brain of Alzheimer's disease and Down's syndrome patients. Therefore, [Pyr3]-Beta-Amyloid-Protein (3-42) is suggested to accumulate in the brain and to trigger the formation of insoluble amyloid β-peptide deposits. Nussbaum et al. studies the Prion-like behaviour and tau-dependent cytotoxicity of the truncated Aβ sequence.Storage/Stability : Shipped at 4°C. Store at -20°C for one year.