Description: Peptide to [Arg15, Asp16, 25, Pro18, 21, 23, Val22, Ile24]-Beta-Amyloid-Protein (15-25) Form: Lyophilized powder CAS Number : 182912-63-6Molecular Formula : C64H94N14O16Molecular Weight : 1315.55Purity : > 95%Chemical Structure : Arg-Asp-Leu-Pro-Phe-Phe-Pro-Val-Pro-Ile-AspApplication : The undecapeptide RDLPFFPVPID (iAβ11) has a similar degree of hydrophobicity as the native amyloid β-peptide (Aβ), but with a low propensity to adopt a β-sheet conformation. It is therefore called anti-β-sheet peptide or β-sheet inhibitor. iAβ11 binds to Aβ, inhibits Aβ fibril formation and partially disaggregates preformed fibrils in vitro. This anti-β-sheet peptide may serve as a starting point to design inhibitors of amyloidogenesis in vivo.Storage/Stability : Shipped at 4°C. Store at -20°C for one year.

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