Description: Peptide to Ac-[Cys (Acm) 33, 42]-EGF (33-42) amide (Mouse) Form: Lyophilized powder CAS Number : 122053-92-3Molecular Formula : C51H82N16O17S2Molecular Weight : 1255.45Purity : > 95%Chemical Structure : Ac-Cys(Acm)-Val-Ile-Gly-Tyr-Ser-Gly-Asp-Arg-Cys(Acm)-NH2Application : This EGF-derived peptide is known as a laminin antagonist. It blocks the stimulatory effects of laminin in cell motility and chick angiogenesis. This peptide binds to a breast cancer- and endothelial cell-associated receptor, which is specific for residues 925 to 933 of the laminin B1 chain. The IC₅₀ values for displacement of laminin are in the range of 1-3 nM, depending on the cells. This peptide has an antimetastatic potential.Storage/Stability : Shipped at 4°C. Store at -20°C for one year.

•