Description: Peptide to [Asn670, Leu671]-APP770 (667-675) Form: Lyophilized powder CAS Number : 150234-52-9Molecular Formula : C44H66N10O18Molecular Weight : 1023.07Purity : > 95%Chemical Structure : Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-PheApplication : SEVNLDAEF corresponds to the mutant junctional sequence of the amyloid precursor protein (APP) found in a Swedish family with early-onset Alzheimer's disease, therefore referred to as the 'Swedish' mutation (K670N/M671L). The peptide has been used for assaying cleavage at leucine-aspartate by cathepsin G and chymotrypsin, whereas neither cathepsin B, D nor L generated any products.Storage/Stability : Shipped at 4°C. Store at -20°C for one year.