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[Asn670, Leu671]-APP770 (667-675) CCP1624
Product Name[Asn670, Leu671]-APP770 (667-675)
Cat No: CCP1624
Source: Synthetic
Reactivity:
Applications:
*Application Key:
E- ELISA, WB - Western blot, IH - Immunohistochemistry, IF - Immunofluorescence, FC - Flow cytometry, IC - Immunocytochemistry, IP - Immunoprecipitation, ChIP - Chromatin Immunoprecipitation, EMSA - Electrophoretic Mobility Shift Assay, BL - Blocking, SE - Sandwich ELISA, CBE - Cell-based ELISA, RNAi - RNA interference
*Species Reactivity Key:
H - Human, M - Mouse, R - Rat, B - Bovine, C - Chicken, D - Dog, G - Goat, Mk - Monkey, P - Pig, Rb - Rabbit, S - Sheep, Z - Zebrafish
Size
Price
1 mg
$66
5 mg
$198
10 mg
$330
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Description: Peptide to [Asn670, Leu671]-APP770 (667-675)
Form: Lyophilized powder
CAS Number : 150234-52-9
Molecular Formula : C44H66N10O18
Molecular Weight : 1023.07
Purity : > 95%
Chemical Structure : Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe
Application : SEVNLDAEF corresponds to the mutant junctional sequence of the amyloid precursor protein (APP) found in a Swedish family with early-onset Alzheimer's disease, therefore referred to as the 'Swedish' mutation (K670N/M671L). The peptide has been used for assaying cleavage at leucine-aspartate by cathepsin G and chymotrypsin, whereas neither cathepsin B, D nor L generated any products.
Storage/Stability : Shipped at 4°C. Store at -20°C for one year.
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