Description: Peptide to [Pyr11]-Beta-Amyloid-Protein (11-40) Form: Lyophilized powder CAS Number : 192377-94-9Molecular Formula : C143H226N38O39SMolecular Weight : 3133.71Purity : > 95%Chemical Structure : Pyr-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-ValApplication : [Pyr11]-Beta-Amyloid-Protein (11-40), the N-terminally truncated isoform of the amyloid β-protein (Aβ) beginning with a pyroglutamate (Pyr) residue at position 11 was used in experiments studying the generality of fibrillogenesis-related helix formation. Comparing the fibrillogenesis kinetics of many of the most important clinically relevant amyloid β-protein alloforms it could be observed that among these peptides (Pyr¹¹)-amyloid β-protein (11-40) exhibited the greatest retardation of fibrillization rate.Storage/Stability : Shipped at 4°C. Store at -20°C for one year.

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