Description: Peptide to Alpha-CGRP (8-37), Rat Form: Lyophilized powder Alternative Names: Calcitonin Gene-Related Peptide I (8-37) (mouse, rat), CGRP-I (8-37) (mouse, rat)CAS Number : 129121-73-9Molecular Formula : C138H224N42O41Molecular Weight : 3127.58Purity : > 95%Chemical Structure : H-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2Application : Alpha-CGRP (8-37), a competitive CGRP1 receptor antagonist, exhibited hypothermic and antinociceptive effects. CGRP-I (8-37) antagonized the effects of amylin and amylin (1-8) on osteoblasts but was substantially less potent in this regard than amylin (8-37). Furthermore, it inhibited the evoked discharge frequency of wide dynamic range neurons in dorsal horn of the spinal cord in rats.Storage/Stability : Shipped at 4°C. Store at -20°C for one year.

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