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Alpha-CGRP (8-37); Rat

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  • Reactivity
  • Applications
Application key: E- ELISA, WB- Western blot, IH- Immunohistochemistry, IF- Immunofluorescence, FC- Flow cytometry, IC- Immunocytochemistry, IP- Immunoprecipitation, ChIP- Chromatin Immunoprecipitation, EMSA- Electrophoretic Mobility Shift Assay, BL- Blocking, SE- Sandwich ELISA, CBE- Cell-based ELISA, RNAi- RNA interference

Species reactivity key: H- Human, M- Mouse, R- Rat, B- Bovine, C- Chicken, D- Dog, G- Goat, Mk- Monkey, P- Pig, Rb- Rabbit, S- Sheep, Z- Zebrafish
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Description Peptide to Alpha-CGRP (8-37); Rat
Form Lyophilized powder
Alternative Names Calcitonin Gene-Related Peptide I (8-37) (mouse; rat); CGRP-I (8-37) (mouse; rat)
CAS Number 129121-73-9
Molecular Formula C138H224N42O41
Molecular Weight 3127.58
Purity > 95%
Chemical Structure H-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2
Application Alpha-CGRP (8-37) a competitive CGRP1 receptor antagonist exhibited hypothermic and antinociceptive effects. CGRP-I (8-37) antagonized the effects of amylin and amylin (1-8) on osteoblasts but was substantially less potent in this regard than amylin (8-37). Furthermore it inhibited the evoked discharge frequency of wide dynamic range neurons in dorsal horn of the spinal cord in rats.
Storage/Stability Shipped at 4 C. Store at -20 C for one year.
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For research purposes only, not for human use
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