Description:Rabbit polyclonal antibody to CD61 (Phospho-Y773)Immunogen:KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding Y773 of human CD61 protein. The exact sequence is proprietary.Purification:The antibody was purified by immunogen affinity chromatography.Clonality:PolyclonalForm:Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.Dilution:WB (1/500 - 1/1000), IH (1/100 - 1/200)Gene Symbol:ITGB3Alternative Names:GP3A; Integrin beta-3; Platelet membrane glycoprotein IIIa; GPIIIa; CD61
Entrez Gene (Human):
3690;
Entrez Gene (Mouse):
16416;
SwissProt (Human):
P05106;
SwissProt (Mouse):
O54890;
Storage/Stability:Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
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Western blot analysis of CD61 (Phospho-Y773) expression in HUVEC (A), Raw264.7 (B) whole cell lysates. (Predicted band size: 87 kD; Observed band size: 130 kD)
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Immunohistochemical analysis of CD61 (Phospho-Y773) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
JAM-A protects from thrombosis by suppressing integrin aIIbß3-dependent outside-in signaling in platelets
Dual mechanism of integrin aIIbß3 closure in procoagulant platelets
Carbon disulfide exposure at peri-implantation disrupts embryo implantation by decreasing integrin ß3 expression in the uterine tissue of pregnant mice