Description:Rabbit polyclonal antibody to KAT7Immunogen:KLH-conjugated synthetic peptide encompassing a sequence within the center region of human KAT7. The exact sequence is proprietary.Purification:The antibody was purified by immunogen affinity chromatography.Clonality:PolyclonalForm:Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.Dilution:WB (1/500 - 1/1000), IF/IC (1/50 - 1/200), IP (1/10 - 1/100)Gene Symbol:KAT7Alternative Names:HBO1; HBOa; MYST2; Histone acetyltransferase KAT7; Histone acetyltransferase binding to ORC1; Lysine acetyltransferase 7; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; MYST-2
Entrez Gene (Human):
11143;
Entrez Gene (Mouse):
217127;
Entrez Gene (Rat):
303470;
SwissProt (Human):
O95251;
SwissProt (Mouse):
Q5SVQ0;
SwissProt (Rat):
Q810T5;
Storage/Stability:Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
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Western blot analysis of KAT7 expression in HepG2 (A), MCF7 (B) whole cell lysates. (Predicted band size: 70 kD; Observed band size: 83 kD)
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Immunofluorescent analysis of KAT7 staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
An expanded Oct4 interaction network: implications for stem cell biology, development, and disease
SCF(Fbxw15) mediates histone acetyltransferase binding to origin recognition complex (HBO1) ubiquitin-proteasomal degradation to regulate cell proliferation
Exchange of associated factors directs a switch in HBO1 acetyltransferase histone tail specificity