Description:Rabbit polyclonal antibody to MMP14Immunogen:KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human MMP14. The exact sequence is proprietary.Purification:The antibody was purified by immunogen affinity chromatography.Clonality:PolyclonalForm:Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.Dilution:WB (1/500 - 1/1000), IH (1/100 - 1/200)Gene Symbol:MMP14Alternative Names:Matrix metalloproteinase-14; MMP-14; MMP-X1; Membrane-type matrix metalloproteinase 1; MT-MMP 1; MTMMP1; Membrane-type-1 matrix metalloproteinase; MT1-MMP; MT1MMP
Entrez Gene (Human):
4323;
Entrez Gene (Mouse):
17387;
Entrez Gene (Rat):
81707;
SwissProt (Human):
P50281;
SwissProt (Mouse):
P53690;
SwissProt (Rat):
Q10739;
Storage/Stability:Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
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Western blot analysis of MMP14 expression in mouse brain (A), rat brain (B) whole cell lysates. (Predicted band size: 65 kD; Observed band size: 63 kD)
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Immunohistochemical analysis of MMP14 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development
CC chemokine receptor 5 deletion impairs macrophage activation and induces adverse remodeling following myocardial infarction
Matrix metalloproteinase 14 in the zebrafish: an eye on retinal and retinotectal development