Description:Rabbit polyclonal antibody to GLUR2Immunogen:KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human GLUR2. The exact sequence is proprietary.Purification:The antibody was purified by immunogen affinity chromatography.Clonality:PolyclonalForm:Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.Dilution:WB (1/500 - 1/1000), IH (1/50 - 1/100)Gene Symbol:GRIA2Alternative Names:GLUR2; Glutamate receptor 2; GluR-2; AMPA-selective glutamate receptor 2; GluR-B; GluR-K2; Glutamate receptor ionotropic, AMPA 2; GluA2
Entrez Gene (Human):
2891;
Entrez Gene (Mouse):
14800;
Entrez Gene (Rat):
29627;
SwissProt (Human):
P42262;
SwissProt (Mouse):
P23819;
SwissProt (Rat):
P19491;
Storage/Stability:Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
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Western blot analysis of GLUR2 expression in mouse brain (A), rat brain (B) whole cell lysates. (Predicted band size: 98 kD; Observed band size: 100 kD)
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Immunohistochemical analysis of GLUR2 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
AMPA/kainate glutamate receptors contribute to inflammation, degeneration and pain related behaviour in inflammatory stages of arthritis