Description:Rabbit polyclonal antibody to Adenylate Cyclase 1Immunogen:KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Adenylate Cyclase 1. The exact sequence is proprietary.Purification:The antibody was purified by immunogen affinity chromatography.Clonality:PolyclonalForm:Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.Dilution:WB (1/500 - 1/1000), IH (1/100 - 1/200)Gene Symbol:ADCY1Alternative Names:Adenylate cyclase type 1; ATP pyrophosphate-lyase 1; Adenylate cyclase type I; Adenylyl cyclase 1; Ca(2+)/calmodulin-activated adenylyl cyclase
Entrez Gene (Human):
107;
Entrez Gene (Mouse):
432530;
SwissProt (Human):
Q08828;
SwissProt (Mouse):
O88444;
Storage/Stability:Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
-
Western blot analysis of Adenylate Cyclase 1 expression in MCF7 (A), C6 (B) whole cell lysates. (Predicted band size: 123 kD; Observed band size: 130 kD)
-
Immunohistochemical analysis of Adenylate Cyclase 1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Multiple Ca2+-dependent mechanisms regulate L-type Ca2+ current in retinal amacrine cells