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CCP1724
Product Name:[D-Arg1, D-Trp5, 7, 9, Leu11]-Substance P
Cat No:CCP1724
Source:Synthetic
Reactivity:
Applications:
*Application Key:
H - Human, M - Mouse, R - Rat, B - Bovine, C - Chicken, D - Dog, G - Goat, Mk - Monkey, P - Pig, Rb - Rabbit, S - Sheep, Z - Zebrafish
*Species Reactivity Key:
E- ELISA, WB - Western blot, IH - Immunohistochemistry, IF - Immunofluorescence, FC - Flow cytometry, IC - Immunocytochemistry, IP - Immunoprecipitation, ChIP - Chromatin Immunoprecipitation, EMSA - Electrophoretic Mobility Shift Assay, BL - Blocking, SE - Sandwich ELISA, CBE - Cell-based ELISA, RNAi - RNA interference
Size
Price(USD)
1 mg
90
5 mg
270
10 mg
450
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Description:Peptide to [D-Arg1, D-Trp5, 7, 9, Leu11]-Substance P
Form:Lyophilized powder
CAS Number:122481-75-8
Molecular Formula:C81H110N20O12
Molecular Weight:1555.91
Purity:> 95%
Chemical Structure:D-Arg-Pro-Lys-Pro-D-Trp-Gln-D-Trp-Phe-D-Trp-Leu-Leu-NH2
Application:This substance P analog is a very potent broad-spectrum neuropeptide inhibitor for small cell lung cancer (SCLC) cell growth in vitro (IC₅₀ = 5 µM). Moreover it potently inhibited signal transduction pathways in vitro and significantly delayed the growth of an SCLC xenograft in vivo. It could therefore be of therapeutic value in SCLC.
Storage/Stability:Shipped at 4°C. Store at -20°C for one year.
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