Description:Peptide to [Pyr1]-Apelin-13Form:Lyophilized powder
CAS Number:217082-60-5Molecular Formula:C69H108N22O16SMolecular Weight:1533.85Purity:> 95%Chemical Structure:Pyr-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-PheApplication:The pyroglutamyl form of apelin-13 exhibited a high activity with an EC₅₀ value of 0.30 nM. pERPRLSHKGPMPF is probably the final product of the post-translational modification of apelin and the biologically active endogenous ligand. [Pyr1]-Apelin-13 has been identified as the predominant apelin isoform in the human heart. Pyr-Apelin-13 stimulates glucose utilization in normal and obese insulin-resistant mice. It could be required for the maintenance of insulin sensitivity.Storage/Stability:Shipped at 4°C. Store at -20°C for one year.