Description:Peptide to Ac-[Cys (Acm) 33, 42]-EGF (33-42) amide (Mouse)Form:Lyophilized powder
CAS Number:122053-92-3Molecular Formula:C51H82N16O17S2Molecular Weight:1255.45Purity:> 95%Chemical Structure:Ac-Cys(Acm)-Val-Ile-Gly-Tyr-Ser-Gly-Asp-Arg-Cys(Acm)-NH2Application:This EGF-derived peptide is known as a laminin antagonist. It blocks the stimulatory effects of laminin in cell motility and chick angiogenesis. This peptide binds to a breast cancer- and endothelial cell-associated receptor, which is specific for residues 925 to 933 of the laminin B1 chain. The IC₅₀ values for displacement of laminin are in the range of 1-3 nM, depending on the cells. This peptide has an antimetastatic potential.Storage/Stability:Shipped at 4°C. Store at -20°C for one year.