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CCP1645
Product Name:Ac-[Cys (Acm) 33, 42]-EGF (33-42) amide (Mouse)
Cat No:CCP1645
Source:Synthetic
Reactivity:
Applications:
*Application Key:
H - Human, M - Mouse, R - Rat, B - Bovine, C - Chicken, D - Dog, G - Goat, Mk - Monkey, P - Pig, Rb - Rabbit, S - Sheep, Z - Zebrafish
*Species Reactivity Key:
E- ELISA, WB - Western blot, IH - Immunohistochemistry, IF - Immunofluorescence, FC - Flow cytometry, IC - Immunocytochemistry, IP - Immunoprecipitation, ChIP - Chromatin Immunoprecipitation, EMSA - Electrophoretic Mobility Shift Assay, BL - Blocking, SE - Sandwich ELISA, CBE - Cell-based ELISA, RNAi - RNA interference
Size
Price(USD)
1 mg
78
5 mg
234
10 mg
390
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Description:Peptide to Ac-[Cys (Acm) 33, 42]-EGF (33-42) amide (Mouse)
Form:Lyophilized powder
CAS Number:122053-92-3
Molecular Formula:C51H82N16O17S2
Molecular Weight:1255.45
Purity:> 95%
Chemical Structure:Ac-Cys(Acm)-Val-Ile-Gly-Tyr-Ser-Gly-Asp-Arg-Cys(Acm)-NH2
Application:This EGF-derived peptide is known as a laminin antagonist. It blocks the stimulatory effects of laminin in cell motility and chick angiogenesis. This peptide binds to a breast cancer- and endothelial cell-associated receptor, which is specific for residues 925 to 933 of the laminin B1 chain. The IC₅₀ values for displacement of laminin are in the range of 1-3 nM, depending on the cells. This peptide has an antimetastatic potential.
Storage/Stability:Shipped at 4°C. Store at -20°C for one year.
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