Description:Peptide to [Asn670, Leu671]-APP770 (667-675)Form:Lyophilized powder
CAS Number:150234-52-9Molecular Formula:C44H66N10O18Molecular Weight:1023.07Purity:> 95%Chemical Structure:Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-PheApplication:SEVNLDAEF corresponds to the mutant junctional sequence of the amyloid precursor protein (APP) found in a Swedish family with early-onset Alzheimer's disease, therefore referred to as the 'Swedish' mutation (K670N/M671L). The peptide has been used for assaying cleavage at leucine-aspartate by cathepsin G and chymotrypsin, whereas neither cathepsin B, D nor L generated any products.Storage/Stability:Shipped at 4°C. Store at -20°C for one year.