Description:Peptide to [Pyr11]-Beta-Amyloid-Protein (11-40)Form:Lyophilized powder
CAS Number:192377-94-9Molecular Formula:C143H226N38O39SMolecular Weight:3133.71Purity:> 95%Chemical Structure:Pyr-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-ValApplication:[Pyr11]-Beta-Amyloid-Protein (11-40), the N-terminally truncated isoform of the amyloid β-protein (Aβ) beginning with a pyroglutamate (Pyr) residue at position 11 was used in experiments studying the generality of fibrillogenesis-related helix formation. Comparing the fibrillogenesis kinetics of many of the most important clinically relevant amyloid β-protein alloforms it could be observed that among these peptides (Pyr¹¹)-amyloid β-protein (11-40) exhibited the greatest retardation of fibrillization rate.Storage/Stability:Shipped at 4°C. Store at -20°C for one year.