Description：Peptide to Thrombin Receptor AgonistForm：Lyophilized powderAlternative Names：Thrombin Receptor Activator Peptide 14, PAR-1 (1-14) (human), Proteinase Activated Receptor 1 (1-14) (human), Thrombin Receptor (1-14) (human), Coagulation Factor II Receptor (1-14) (human) CAS Number：137339-65-2Molecular Formula：C81H118N20O23Molecular Weight：1739.96Purity：> 95%Chemical Structure：H-Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe-OHApplication：Cloning and expression of a functional human thrombin receptor have revealed a protein with seven transmembrane domains and a large extracellular amino-terminal extension. Thrombin cleaves within this extension, thereby creating a new receptor amino-terminus that functions as a tethered ligand and activates the receptor. A 14-amino acid peptide mimicking this new amino-terminus has been found to be a potent thrombin receptor activator as well as an effective agonist for platelet activation.Storage/Stability：Shipped at 4°C. Store at -20°C for one year.

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