Description:Peptide to Stresscopin-Related Peptide, HumanForm:Lyophilized powderAlternative Names:SRP (human)
CAS Number:348626-74-4Molecular Formula:C205H358N68O57Molecular Weight:4687.56Purity:> 95%Chemical Structure:H-His-Pro-Gly-Ser-Arg-Ile-Val-Leu-Ser-Leu-Asp-Val-Pro-Ile-Gly-Leu-Leu-Gln-Ile-Leu-Leu-Glu-Gln-Ala-Arg-Ala-Arg-Ala-Ala-Arg-Glu-Gln-Ala-Thr-Thr-Asn-Ala-Arg-Ile-Leu-Ala-Arg-Val-NH2Application:Stresscopin-related peptide is a specific ligand for the corticotropin-releasing hormone receptor type 2 (CRHR2). Transcripts are expressed in brain and multiple peripheral tissues. Intraperitoneal injections of stresscopin-related peptide (human) suppresses heat-induced edema formation in anesthetized rats. It also decreases food intake and exhibits an inhibitory effect on gastric emptying activity. This CRHR2 agonist might represent an endogenous ligand for maintaining homeostasis after stress.Storage/Stability:Shipped at 4°C. Store at -20°C for one year.