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CCP1360
Product Name:Orexin B, Human
Cat No:CCP1360
Source:Synthetic
Reactivity:
Applications:
*Application Key:
H - Human, M - Mouse, R - Rat, B - Bovine, C - Chicken, D - Dog, G - Goat, Mk - Monkey, P - Pig, Rb - Rabbit, S - Sheep, Z - Zebrafish
*Species Reactivity Key:
E- ELISA, WB - Western blot, IH - Immunohistochemistry, IF - Immunofluorescence, FC - Flow cytometry, IC - Immunocytochemistry, IP - Immunoprecipitation, ChIP - Chromatin Immunoprecipitation, EMSA - Electrophoretic Mobility Shift Assay, BL - Blocking, SE - Sandwich ELISA, CBE - Cell-based ELISA, RNAi - RNA interference
Size
Price(USD)
1 mg
258
5 mg
774
10 mg
1290
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Description:Peptide to Orexin B, Human
Form:Lyophilized powder
Alternative Names:Hypocretin-2 (human)
CAS Number:205640-91-1
Molecular Formula:C123H212N44O35S
Molecular Weight:2899.4
Purity:> 95%
Chemical Structure:Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
Application:Like orexin A, orexin B is a hypothalamic neuropeptide regulating the feeding behavior. Central administration of orexin B to rats stimulated food consumption in a similar manner to orexin A, but the effect did not last as long as that of orexin A. The affinity of orexin B for the OX₁ receptor is significantly lower (IC₅₀ = 240 nM) than that of orexin A. Binding affinities for the OX₂ receptor are similar for orexin A and B (IC₅₀ = 38 nM and 36 nM, respectively, for displacement of radiolabeled orexin A bound to the receptor).
Storage/Stability:Shipped at 4°C. Store at -20°C for one year.
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