Description:Peptide to M40Form:Lyophilized powder
CAS Number:143896-17-7Molecular Formula:C94H145N23O24Molecular Weight:1981.34Purity:> 95%Chemical Structure:H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Ala-Leu-Ala-Leu-Ala-NH2Application:M40, a peptide containing the N-terminal galanin sequence (1-13), is an antagonist of the galanin receptor. M40 significantly antagonized galanin-induced feeding behavior at doses approximately equimolar to the active doses of rat galanin. M40 inhibited the binding of (¹²⁵I-Tyr²⁶)-galanin (porcine) in rat hypothalamic membranes with an IC₅₀ value of 15 nM.Storage/Stability:Shipped at 4°C. Store at -20°C for one year.