Description:Peptide to Histatin 5Form:Lyophilized powder
CAS Number:104339-66-4Molecular Formula:C133H195N51O33Molecular Weight:3036.36Purity:> 95%Chemical Structure:H-Asp-Ser-His-Ala-Lys-Arg-His-His-Gly-Tyr-Lys-Arg-Lys-Phe-His-Glu-Lys-His-His-Ser-His-Arg-Gly-Tyr-OHApplication:Histatin-5, a salivary polypeptide, has been shown to inhibit clostripain (IC₅₀ = 800 nM) and a trypsin-like protease produced by Bacteroides gingivalis (IC₅₀ = 55 nM). Other proteases, however, have not been inhibited by histatin-5. This peptide was therefore suggested to be a preventive against periodontal disease. Histatin-5 exhibits antimicrobial and a distinct antifungal activity targetting fungal mitochondria.Storage/Stability:Shipped at 4°C. Store at -20°C for one year.