Description:Peptide to HelodorminForm:Lyophilized powder
CAS Number:89468-62-2Molecular Formula:C176H285N47O49Molecular Weight:3843.47Purity:> 95%Chemical Structure:H-His-Ser-Asp-Ala-Ile-Phe-Thr-Glu-Glu-Tyr-Ser-Lys-Leu-Leu-Ala-Lys-Leu-Ala-Leu-Gln-Lys-Tyr-Leu-Ala-Ser-Ile-Leu-Gly-Ser-Arg-Thr-Ser-Pro-Pro-Pro-NH2Application:Helodermin was originally isolated from the venom of Gila monster (Heloderma suspectum). A high degree of sequence similarities to secretin, VIP, PHI, and GRF from mammal and bird was observed over the entire N-terminal (1-27) sequence. The isolation of helodermin was the first demonstration of the existence of a secretin/VIP-related peptide in an animal that is neither mammal nor bird. Among all known VIP-related peptides, helodermin was the most potent in stimulating cAMP production by NCI-H345 cell line.Storage/Stability:Shipped at 4°C. Store at -20°C for one year.