Description:Peptide to Apelin-13, Human, BovineForm:Lyophilized powder
CAS Number:217082-58-1Molecular Formula:C69H111N23O16SMolecular Weight:1550.86Purity:> 95%Chemical Structure:H-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OHApplication:Apelin-13, generated from apelin-36, is an endogenous peptide ligand for the human APJ receptor, a putative receptor protein related to the angiotensin receptor (AT1). Apelin-13 exerted an acidification-rate-promoting activity in the CHO cells expressing the APJ receptor with a median effective concentration (EC₅₀) value of 0.37 nM. In a study of Valle et al. chronic central administration of apelin-13 over 10 days increased food intake, body weight, locomotor activity and body temperature in C57BL/6 mice.Storage/Stability:Shipped at 4°C. Store at -20°C for one year.