Description:Peptide to Amylin (IAPP)(Feline)Form:Lyophilized powder
Molecular Formula:C165H270N52O54S2Molecular Weight:3910.45Purity:> 95%Chemical Structure:H-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Ile-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Ala-Ile-Leu-Ser-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2 (Disulfide bridge Cys2-Cys7)Application:Endogenous peptide secreted by pancreatic β-cells. Potently activates amylin, calcitonin (EC50 = 0.67 nM), CGRP and adrenomedullin receptors. Highly potently inhibitor of insulin-stimulated glucose uptake in skeletal muscle cells (IC50 = 12 pM). Implicated in type II diabetes.Storage/Stability:Shipped at 4°C. Store at -20°C for one year.